Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens
Abstract Introduction We conducted an evaluation of capsular bag performance of the Clareon CNA0T0 intraocular lens (IOL), focusing on postoperative anterior chamber depth (ACD), IOL tilt, and IOL decentration. Methods Inclusion criteria were bilateral age-related cataract and the ability to provide...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Adis, Springer Healthcare
2024-12-01
|
| Series: | Ophthalmology and Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s40123-024-01075-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585992163295232 |
|---|---|
| author | Klemens Waser Klaus Straßmair Leon Pomberger Haidar Khalil Peter Laubichler Matthias Bolz Nino Hirnschall |
| author_facet | Klemens Waser Klaus Straßmair Leon Pomberger Haidar Khalil Peter Laubichler Matthias Bolz Nino Hirnschall |
| author_sort | Klemens Waser |
| collection | DOAJ |
| description | Abstract Introduction We conducted an evaluation of capsular bag performance of the Clareon CNA0T0 intraocular lens (IOL), focusing on postoperative anterior chamber depth (ACD), IOL tilt, and IOL decentration. Methods Inclusion criteria were bilateral age-related cataract and the ability to provide informed consent. Exclusion criteria were prior surgeries, combined surgeries, and conditions posing a risk for postoperative capsular bag instability. Preoperative and 8-week postoperative assessments included optical biometry and high-resolution anterior segment optical coherence tomography (OCT). Subjective refraction was conducted only at 8 weeks postoperative visit. Results In the first analysis, 49 right eyes of 49 patients were included. Mean preoperative and postoperative ACD were 3.10 and 4.69 mm, respectively. Mean preoperative tilt was 4.77°, increasing to 5.06° postoperatively. Preoperative decentration was 0.16 mm, increasing to 0.26 mm postoperatively. Absolute refractive error (ARE) was + 0.31D, with 81% of eyes within ± 0.5D limits. In analysis II (98 eyes of 49 patients), both eyes showed a moderate correlation in IOL tilt (Pearson correlation coefficient: 0.27, p = 0.061) and a low correlation in IOL decentration (Pearson correlation coefficient: 0.02, p = 0.892) and ARE (Spearman: 0.15, p = 305) between right and left eyes of the same patient. Conclusions The Clareon CNA0T0 IOL demonstrated high mechanical stability, with low postoperative tilt and decentration values, resulting in excellent refractive outcomes and visual acuity. These findings confirm the IOL’s high stability within the capsular bag and effectiveness in minimizing postoperative refractive error, requiring only minor A-constant adjustments for optimal cataract surgery outcomes. Trial Registration NCT06595693. |
| format | Article |
| id | doaj-art-697c2d335ccf49a0975f99fb13f2c996 |
| institution | Kabale University |
| issn | 2193-8245 2193-6528 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Ophthalmology and Therapy |
| spelling | doaj-art-697c2d335ccf49a0975f99fb13f2c9962025-01-26T12:18:43ZengAdis, Springer HealthcareOphthalmology and Therapy2193-82452193-65282024-12-0114229530810.1007/s40123-024-01075-xCapsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular LensKlemens Waser0Klaus Straßmair1Leon Pomberger2Haidar Khalil3Peter Laubichler4Matthias Bolz5Nino Hirnschall6Kepler University ClinicKepler University ClinicKepler University ClinicKepler University ClinicKepler University ClinicKepler University ClinicKepler University ClinicAbstract Introduction We conducted an evaluation of capsular bag performance of the Clareon CNA0T0 intraocular lens (IOL), focusing on postoperative anterior chamber depth (ACD), IOL tilt, and IOL decentration. Methods Inclusion criteria were bilateral age-related cataract and the ability to provide informed consent. Exclusion criteria were prior surgeries, combined surgeries, and conditions posing a risk for postoperative capsular bag instability. Preoperative and 8-week postoperative assessments included optical biometry and high-resolution anterior segment optical coherence tomography (OCT). Subjective refraction was conducted only at 8 weeks postoperative visit. Results In the first analysis, 49 right eyes of 49 patients were included. Mean preoperative and postoperative ACD were 3.10 and 4.69 mm, respectively. Mean preoperative tilt was 4.77°, increasing to 5.06° postoperatively. Preoperative decentration was 0.16 mm, increasing to 0.26 mm postoperatively. Absolute refractive error (ARE) was + 0.31D, with 81% of eyes within ± 0.5D limits. In analysis II (98 eyes of 49 patients), both eyes showed a moderate correlation in IOL tilt (Pearson correlation coefficient: 0.27, p = 0.061) and a low correlation in IOL decentration (Pearson correlation coefficient: 0.02, p = 0.892) and ARE (Spearman: 0.15, p = 305) between right and left eyes of the same patient. Conclusions The Clareon CNA0T0 IOL demonstrated high mechanical stability, with low postoperative tilt and decentration values, resulting in excellent refractive outcomes and visual acuity. These findings confirm the IOL’s high stability within the capsular bag and effectiveness in minimizing postoperative refractive error, requiring only minor A-constant adjustments for optimal cataract surgery outcomes. Trial Registration NCT06595693.https://doi.org/10.1007/s40123-024-01075-xCapsular bag performanceClareon IOL CNA0T0Anterior chamber depthTiltDecentration |
| spellingShingle | Klemens Waser Klaus Straßmair Leon Pomberger Haidar Khalil Peter Laubichler Matthias Bolz Nino Hirnschall Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens Ophthalmology and Therapy Capsular bag performance Clareon IOL CNA0T0 Anterior chamber depth Tilt Decentration |
| title | Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens |
| title_full | Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens |
| title_fullStr | Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens |
| title_full_unstemmed | Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens |
| title_short | Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens |
| title_sort | capsular bag performance of a novel hydrophobic single piece intraocular lens |
| topic | Capsular bag performance Clareon IOL CNA0T0 Anterior chamber depth Tilt Decentration |
| url | https://doi.org/10.1007/s40123-024-01075-x |
| work_keys_str_mv | AT klemenswaser capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens AT klausstraßmair capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens AT leonpomberger capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens AT haidarkhalil capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens AT peterlaubichler capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens AT matthiasbolz capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens AT ninohirnschall capsularbagperformanceofanovelhydrophobicsinglepieceintraocularlens |