Machine learning assisted immune profiling of COPD identifies a unique emphysema subtype independent of GOLD stage

Machine learning assisted immune profiling of COPD identifies a unique emphysema subtype independent of GOLD stage

Summary: Chronic obstructive pulmonary disease (COPD) is a severe, progressive, and heterogeneous disease with a poor outcome. Inflammation plays a central role in disease pathogenesis; however, the interplay between immune changes and disease heterogeneity has been difficult to unravel. We performe...

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Main Authors: Natalie Bordag, Katharina Jandl, Ayu Hutami Syarif, Jürgen Gindlhuber, Diana Schnoegl, Ayse Ceren Mutgan, Vasile Foris, Konrad Hoetzenecker, Panja Maria Boehm, Robab Breyer-Kohansal, Katarina Zeder, Gregor Gorkiewicz, Francesca Polverino, Slaven Crnkovic, Grazyna Kwapiszewska, Leigh Matthew Marsh
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
respiratory medicine
machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225012271
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