NLRP3 inflammasome activation and disruption of IRS-1/PI3K/AKT signaling: Potential mechanisms of arsenic-induced pancreatic beta cells dysfunction in rats
Environmental exposure to arsenic is associated with significant health risks, including diabetogenic effects linked to pancreatic dysfunction. The NOD-like receptor protein 3 (NLRP3) inflammasome has been implicated in various metabolic abnormalities; however, its specific role in arsenic-induced p...
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Main Authors: | Yonglian Liu, Wenjuan Wang, Bing Liang, Zhonglan Zou, Aihua Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Ecotoxicology and Environmental Safety |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S014765132401580X |
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