Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital
Background: Inflammatory bowel disease (IBD)` may affect organs outside the intestines, it is called extraintestinal manifestations of IBD. Data on the prevalence of mu-cocutaneous manifestations in IBD patients are very limited, therefore, the aim of this study was to assess the prevalence of skin...
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Vilnius University Press
2024-09-01
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| Series: | Acta Medica Lituanica |
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| Online Access: | https://www.journals.vu.lt/AML/article/view/35011 |
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| author | Ieva Renata Jonaitytė Vita Karpavičiūtė Gediminas Kiudelis Juozas Kupčinskas Laimas Jonaitis |
| author_facet | Ieva Renata Jonaitytė Vita Karpavičiūtė Gediminas Kiudelis Juozas Kupčinskas Laimas Jonaitis |
| author_sort | Ieva Renata Jonaitytė |
| collection | DOAJ |
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Background: Inflammatory bowel disease (IBD)` may affect organs outside the intestines, it is called extraintestinal manifestations of IBD. Data on the prevalence of mu-cocutaneous manifestations in IBD patients are very limited, therefore, the aim of this study was to assess the prevalence of skin and mucosal lesions and to determine the relationship with demographic factors, clinical features, and systemic treatment.
Materials and methods: Prospective study included 162 out-patients with IBD who were managed in the tertiary care center. Ulcerative colitis (UC) was diagnosed in 117 patients, Crohn‘s disease (CD) in 45. Patients completed the questionnaire containing demographic and IBD data, questions about mucocutaneous lesions (in past or present state).
Results: Overall mucocutaneous lesions were reported by 48.1% of IBD patients. Skin lesions were reported by 40.7% of patients, oral mucosal lesions were reported by 16.7%, without significant differences between sexes or IBD types. In 47 (29%) of patients, skin lesions appeared together with IBD or during the course of the disease. The most common skin lesions were psoriasis (8.0%), erythema nodosum (5.6%), pyoderma gangrenosum and acne (3.7% each). UC patients mostly reported about psoriasis (9.4%), while CD patients about erythema nodosum (11.1%). There were more frequent skin lesions in patients with more extensive UC type (p = 0.01), while no difference was noticed between different types of CD. The average duration of IBD in patients with skin lesions was similar to those without lesions (9.3±6.7 vs. 9.4±6.7 years).
Conclusions: Mucocutaneous lesions were reported by 48.1% of inflammatory bowel disease patients. The frequency of mucocutaneous lesions does not differ significantly between UC and CD, and a longer duration of illness is not a predictive factor for the appearance of lesions. More extensive UC is related to higher frequency of skin lesions.
Erratum note
The title, author's name, and abstract have been updated to reflect the correct information following a typographical error during typesetting. We apologize for any inconvenience caused by these errors. Corrections were made on 2024-09-01.
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| format | Article |
| id | doaj-art-68fd6e32ddbb492693e624b1c9f2aaae |
| institution | Kabale University |
| issn | 1392-0138 2029-4174 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Acta Medica Lituanica |
| spelling | doaj-art-68fd6e32ddbb492693e624b1c9f2aaae2025-01-20T18:07:53ZengVilnius University PressActa Medica Lituanica1392-01382029-41742024-09-0131110.15388/Amed.2024.31.1.23Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University HospitalIeva Renata Jonaitytė 0https://orcid.org/0009-0002-5541-5089Vita Karpavičiūtė1https://orcid.org/0009-0009-2513-7269Gediminas Kiudelis2https://orcid.org/0000-0001-5945-8284Juozas Kupčinskas3https://orcid.org/0000-0002-8760-7416Laimas Jonaitis4https://orcid.org/0000-0001-9086-3675Vilnius University Hospital Santaros klinikos, Center of Dermatovenerology; Lithuanian University of Health Sciences, Department of Gastroenterology, Kaunas, LithuaniaLithuanian University of Health Sciences, Department of Gastroenterology, Kaunas, LithuaniaLithuanian University of Health Sciences, Department of Gastroenterology, Kaunas, LithuaniaLithuanian University of Health Sciences, Department of Gastroenterology, Kaunas, LithuaniaLithuanian University of Health Sciences, Department of Gastroenterology, Kaunas, Lithuania Background: Inflammatory bowel disease (IBD)` may affect organs outside the intestines, it is called extraintestinal manifestations of IBD. Data on the prevalence of mu-cocutaneous manifestations in IBD patients are very limited, therefore, the aim of this study was to assess the prevalence of skin and mucosal lesions and to determine the relationship with demographic factors, clinical features, and systemic treatment. Materials and methods: Prospective study included 162 out-patients with IBD who were managed in the tertiary care center. Ulcerative colitis (UC) was diagnosed in 117 patients, Crohn‘s disease (CD) in 45. Patients completed the questionnaire containing demographic and IBD data, questions about mucocutaneous lesions (in past or present state). Results: Overall mucocutaneous lesions were reported by 48.1% of IBD patients. Skin lesions were reported by 40.7% of patients, oral mucosal lesions were reported by 16.7%, without significant differences between sexes or IBD types. In 47 (29%) of patients, skin lesions appeared together with IBD or during the course of the disease. The most common skin lesions were psoriasis (8.0%), erythema nodosum (5.6%), pyoderma gangrenosum and acne (3.7% each). UC patients mostly reported about psoriasis (9.4%), while CD patients about erythema nodosum (11.1%). There were more frequent skin lesions in patients with more extensive UC type (p = 0.01), while no difference was noticed between different types of CD. The average duration of IBD in patients with skin lesions was similar to those without lesions (9.3±6.7 vs. 9.4±6.7 years). Conclusions: Mucocutaneous lesions were reported by 48.1% of inflammatory bowel disease patients. The frequency of mucocutaneous lesions does not differ significantly between UC and CD, and a longer duration of illness is not a predictive factor for the appearance of lesions. More extensive UC is related to higher frequency of skin lesions. Erratum note The title, author's name, and abstract have been updated to reflect the correct information following a typographical error during typesetting. We apologize for any inconvenience caused by these errors. Corrections were made on 2024-09-01. https://www.journals.vu.lt/AML/article/view/35011ulcerative colitisCrohn’s diseaseextraintestinal manifestationskin lesionsmucocutaneous lesions |
| spellingShingle | Ieva Renata Jonaitytė Vita Karpavičiūtė Gediminas Kiudelis Juozas Kupčinskas Laimas Jonaitis Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital Acta Medica Lituanica ulcerative colitis Crohn’s disease extraintestinal manifestation skin lesions mucocutaneous lesions |
| title | Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital |
| title_full | Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital |
| title_fullStr | Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital |
| title_full_unstemmed | Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital |
| title_short | Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital |
| title_sort | mucocutaneous manifestations reported by inflammatory bowel disease patients in university hospital |
| topic | ulcerative colitis Crohn’s disease extraintestinal manifestation skin lesions mucocutaneous lesions |
| url | https://www.journals.vu.lt/AML/article/view/35011 |
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