Effect of clindamycin and a live biotherapeutic on the reproductive outcomes of IVF patients with abnormal vaginal microbiota: protocol for a double-blind, placebo-controlled multicentre trial

Effect of clindamycin and a live biotherapeutic on the reproductive outcomes of IVF patients with abnormal vaginal microbiota: protocol for a double-blind, placebo-controlled multicentre trial

Introduction Recent studies in in vitro fertilisation (IVF) patients have associated abnormal vaginal microbiota (AVM) with poor clinical pregnancy rates of 6%–9% per embryo transfer. The biological plausibility for this finding is hypothesised to be ascending infection to the endometrium which in t...

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Main Authors: Niels Uldbjerg, Nina La Cour Freiesleben, Anja Pinborg, Peter Humaidan, Henriette Svarre Nielsen, Thor Haahr, Vibeke Hartvig, Anne-Lis Mikkelsen, Thomas Parks, Jørgen Skov Jensen
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/10/e035866.full
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https://bmjopen.bmj.com/content/10/10/e035866.full

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