Nystose attenuates bone loss and promotes BMSCs differentiation to osteoblasts through BMP and Wnt/β-catenin pathway in ovariectomized mice

Nystose attenuates bone loss and promotes BMSCs differentiation to osteoblasts through BMP and Wnt/β-catenin pathway in ovariectomized mice

Increasing the osteogenic differentiation ability and decreasing the adipogenic differentiation ability of bone marrow mesenchymal stem cells (BMSCs) is a potential strategy for the treatment of osteoporosis (OP). Naturally derived oligosaccharides have shown significant anti-osteoporotic effects. N...

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Bibliographic Details
Main Authors: Qi Zhang, Sijing Hu, Jianjun Wu, Peng Sun, Quanlong Zhang, Yang Wang, Qiming Zhao, Ting Han, Luping Qin, Qiaoyan Zhang
Format: Article
Language:English
Published: Tsinghua University Press 2023-03-01
Series:Food Science and Human Wellness
Subjects:
Nystose
Bone marrow mesenchymal stem cell
Osteoblast
Adipocyte
BMP pathway
Wnt/β-catenin pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453022001781
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