Protective effects of Atractylodes macrocephala polysaccharides on acetaminophen-induced liver injury

Protective effects of Atractylodes macrocephala polysaccharides on acetaminophen-induced liver injury

BackgroundDrug-induced liver injury (DILI) is a major clinical concern due to its unpredictable nature and lack of effective therapeutic options.MethodsThis study investigated the hepatoprotective effects of Atractylodes macrocephala polysaccharides (AMPs) in a mouse model of acetaminophen (APAP)-in...

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Main Authors:	Jiali Wu, Biao Jia, Shuai Gong, Yangpeng Li, Jiaqi Wang, Yuqiao Huang, Jiao Guo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	hepatoprotection herbal polysaccharides intestinal microbiota oxidative stress NLRP3 inflammasome
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1583334/full
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