HIV-1 and BLV are insensitive to SERINC5 restriction under the cell-cell infection

HIV-1 and BLV are insensitive to SERINC5 restriction under the cell-cell infection

ABSTRACT Serine incorporator 5 (SERINC5, SER5) suppresses viral cell-free infection. However, its antiviral potency under viral cell-cell infection is not examined yet. Here, we established the in vitro cell-cell infection systems to assess SER5’s antiviral activity on HIV-1 and bovine leukemia viru...

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Bibliographic Details
Main Authors: Changqing Yu, Faming Jiang, Yujing Li, Qiushui Li, Kenzo Tokunaga, Dan Yang, Chao Xu, Nan Li, Sunan Li, Ilyas Khan, Yuanhua Xian, Changyou Xia, He Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:Microbiology Spectrum
Subjects:
serine incorporator 5
retrovirus
HIV-1
BLV
cell-cell
restriction
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02748-24
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