Microbiological contamination in IVF laboratories: A narrative review

In vitro fertilization (IVF) is one of the most used assisted reproductive technology (ART) techniques today. However, the success of IVF procedures heavily relies on maintaining a sterile environment in laboratories. This narrative review examines the effects of microbiological contamination in IVF...

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Main Authors: Sudheer Singh, Nancy Nair, Akash More, Neeraj Vishwakarma, Avanti Kalbande
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Asian Pacific Journal of Reproduction
Subjects:
Online Access:https://journals.lww.com/10.4103/apjr.apjr_168_24
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author Sudheer Singh
Nancy Nair
Akash More
Neeraj Vishwakarma
Avanti Kalbande
author_facet Sudheer Singh
Nancy Nair
Akash More
Neeraj Vishwakarma
Avanti Kalbande
author_sort Sudheer Singh
collection DOAJ
description In vitro fertilization (IVF) is one of the most used assisted reproductive technology (ART) techniques today. However, the success of IVF procedures heavily relies on maintaining a sterile environment in laboratories. This narrative review examines the effects of microbiological contamination in IVF laboratories, exploring its sources, impacts on IVF outcomes, and preventive measures. We conducted a complete literature search using databases such as PubMed and Google Scholar, focusing on studies published within the last fifteen years. Our findings highlight that microbiological contamination can significantly impair embryo quality, reduce implantation and pregnancy rates, and increase the risk of miscarriage and infection. The review also discusses current best practices for contamination prevention and identifies areas for future research. This work emphasizes the critical importance of stringent sterility protocols in IVF laboratories and calls for continued vigilance and innovation in maintaining optimal conditions for assisted reproduction.
format Article
id doaj-art-685eaf19f4e641d5992deac0337e654b
institution Kabale University
issn 2305-0500
2305-0519
language English
publishDate 2025-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Asian Pacific Journal of Reproduction
spelling doaj-art-685eaf19f4e641d5992deac0337e654b2025-02-06T04:53:22ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Reproduction2305-05002305-05192025-01-0114171210.4103/apjr.apjr_168_24Microbiological contamination in IVF laboratories: A narrative reviewSudheer SinghNancy NairAkash MoreNeeraj VishwakarmaAvanti KalbandeIn vitro fertilization (IVF) is one of the most used assisted reproductive technology (ART) techniques today. However, the success of IVF procedures heavily relies on maintaining a sterile environment in laboratories. This narrative review examines the effects of microbiological contamination in IVF laboratories, exploring its sources, impacts on IVF outcomes, and preventive measures. We conducted a complete literature search using databases such as PubMed and Google Scholar, focusing on studies published within the last fifteen years. Our findings highlight that microbiological contamination can significantly impair embryo quality, reduce implantation and pregnancy rates, and increase the risk of miscarriage and infection. The review also discusses current best practices for contamination prevention and identifies areas for future research. This work emphasizes the critical importance of stringent sterility protocols in IVF laboratories and calls for continued vigilance and innovation in maintaining optimal conditions for assisted reproduction.https://journals.lww.com/10.4103/apjr.apjr_168_24in vitro fertilizationassisted reproductive technologiesmicrobial contaminationembryonic arrestinfertility
spellingShingle Sudheer Singh
Nancy Nair
Akash More
Neeraj Vishwakarma
Avanti Kalbande
Microbiological contamination in IVF laboratories: A narrative review
Asian Pacific Journal of Reproduction
in vitro fertilization
assisted reproductive technologies
microbial contamination
embryonic arrest
infertility
title Microbiological contamination in IVF laboratories: A narrative review
title_full Microbiological contamination in IVF laboratories: A narrative review
title_fullStr Microbiological contamination in IVF laboratories: A narrative review
title_full_unstemmed Microbiological contamination in IVF laboratories: A narrative review
title_short Microbiological contamination in IVF laboratories: A narrative review
title_sort microbiological contamination in ivf laboratories a narrative review
topic in vitro fertilization
assisted reproductive technologies
microbial contamination
embryonic arrest
infertility
url https://journals.lww.com/10.4103/apjr.apjr_168_24
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AT nancynair microbiologicalcontaminationinivflaboratoriesanarrativereview
AT akashmore microbiologicalcontaminationinivflaboratoriesanarrativereview
AT neerajvishwakarma microbiologicalcontaminationinivflaboratoriesanarrativereview
AT avantikalbande microbiologicalcontaminationinivflaboratoriesanarrativereview