DKK1 and Its Receptors in Esophageal Adenocarcinoma: A Promising Molecular Target

DKK1 and Its Receptors in Esophageal Adenocarcinoma: A Promising Molecular Target

Esophageal adenocarcinoma (EAC) is an aggressive gastrointestinal (GI) malignancy with increasing incidence. Despite the recent progress in targeted therapies and surgical approaches, the survival rates of esophageal adenocarcinoma patients remain poor. The Dickkopf (DKK) proteins are secretory prot...

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Bibliographic Details
Main Authors: Markos Despotidis, Orestis Lyros, Tatiana S. Driva, Panagiotis Sarantis, Emmanouil I. Kapetanakis, Adam Mylonakis, Andreas Mamilos, Stratigoula Sakellariou, Dimitrios Schizas
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Diagnostics
Subjects:
esophageal adenocarcinoma
DKK proteins
DKK receptors
Wnt signaling pathway
molecular target
Online Access:https://www.mdpi.com/2075-4418/15/1/85
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