Ameliorative effect of curcuminoids in liver fibrosis rat model via regulating GIPC1 gene and modulating MMP-8/TIMP-3 balance mediated by miR-483-5p
Abstract Background Liver fibrosis is a worldwide disease that develops from activation and propagation of hepatic stellate cells, and subsequent extracellular matrix accumulation. Liver fibrosis is associated with multiple pathways, however, the dysregulation of GIPC1 gene (GIPC PDZ domain containi...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2025-01-01
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Series: | Beni-Suef University Journal of Basic and Applied Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43088-024-00590-x |
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