Production of cycloastragenol in metabolically engineered yeast

Cycloastragenol is a bioactive, high-value triterpenoid derived from Astragalus membranaceus. Conventional plant-based extraction and chemical synthesis methods are expensive. To our knowledge, this is the first report on the de novo biosynthesis of cycloastragenol in yeast. The mevalonate pathway w...

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Bibliographic Details
Main Authors: Jingxian Zhang, Peng Xu, Yongjun Wei
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Engineering Microbiology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667370325000414
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