Integrated bioinformatics analysis identifies ALDH18A1 as a prognostic hub gene in glutamine metabolism in lung adenocarcinoma

Abstract Glutamine metabolism is pivotal in cancer biology, profoundly influencing tumor growth, proliferation, and resistance to therapies. Cancer cells often exhibit an elevated dependence on glutamine for essential functions such as energy production, biosynthesis of macromolecules, and maintenan...

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Bibliographic Details
Main Authors: Hao Ren, Deng-Feng Ge, Zi-Chen Yang, Zhen-Ting Cheng, Shou-Xiang Zhao, Bin Zhang
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-024-01698-3
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