Case report: Therapeutic response of front-line cadonilimab plus chemotherapy on patient with advanced lung adenocarcinoma harboring STK11 genetic aberration

Case report: Therapeutic response of front-line cadonilimab plus chemotherapy on patient with advanced lung adenocarcinoma harboring STK11 genetic aberration

The STK11 gene mutation is a common genetic alteration in non-small cell lung cancer (NSCLC) and is significantly associated with poor responses to current immunotherapy regimens. Despite its prevalence, there is currently no established standard for front-line treatment in this subtype of NSCLC, un...

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Main Authors: Du Feng, Huixin Jiang, Gengjia Chen, Wenhui Guan, Lin Yi, Yue Zhu, Yijia Li, Gengda Huang, Bin He, Junlong Tang, Yujie Tang, Jiyuan Zeng, Wensheng Zhou, Jiayu Shi, Zhanhong Xie, Ming Liu, Xiaohong Xie, Xinqing Lin, Chengzhi Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
STK11 mutation
lung adenocarcinoma
case report
cadonilimab
front-line therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1485358/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1485358/full

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