Induction of translation-suppressive G3BP1+ stress granules and interferon-signaling cGAS condensates by transfected plasmid DNA
Plasmid DNA transfection is one of the fundamental tools of biomedical research. Here, we found that plasmid DNA transfection mediated by liposomes activates multiple innate immune responses in several widely used cell lines. Their activations were visible by the detection of stress granules (SG) an...
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Main Authors: | Vladimir Majerciak, Zhi-Ming Zheng |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | hLife |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2949928324000956 |
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