Induction of translation-suppressive G3BP1+ stress granules and interferon-signaling cGAS condensates by transfected plasmid DNA

Plasmid DNA transfection is one of the fundamental tools of biomedical research. Here, we found that plasmid DNA transfection mediated by liposomes activates multiple innate immune responses in several widely used cell lines. Their activations were visible by the detection of stress granules (SG) an...

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Bibliographic Details
Main Authors: Vladimir Majerciak, Zhi-Ming Zheng
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:hLife
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949928324000956
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