Metallothionein 1X is a tumor suppressor gene and inhibits oxidative stress and metastasis in renal cell carcinoma

Metallothionein 1X is a tumor suppressor gene and inhibits oxidative stress and metastasis in renal cell carcinoma

Abstract Metallothioneins 1X (MT1X) is expressed at low levels in renal cell carcinoma (RCC) and correlates with tumor progression, stage, grade and prognosis, but the mechanism of MT1X’s role in renal cell carcinoma is not fully understood at present, and the aim of this study was to investigate th...

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Bibliographic Details
Main Authors: Rui Rui, Cong Huang, Yucai Wu, Heng Guo, Yanqing Gong, Xuesong Li, Liqun Zhou, Shiming He
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Metallothioneins 1X
Renal cell carcinoma
Reactive oxygen species
Epithelial-mesenchymal transition
Trolox
Online Access:https://doi.org/10.1007/s12672-025-02949-7
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https://doi.org/10.1007/s12672-025-02949-7

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