Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes

Abstract Background Diabetes mellitus elevates the risk of developing heart failure and increases associated mortality rates. While the clinical features of diabetic cardiomyopathy have been extensively studied, the effects of diabetes and associated changes in metabolic state on contractile cross-b...

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Bibliographic Details
Main Authors: J. H. Musgrave, J.-C. Han, M.-L. Ward, N. Kang, A. J. Taberner, K. Tran
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cardiovascular Diabetology
Online Access:https://doi.org/10.1186/s12933-025-02820-7
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