The mechanism of Bletilla striata inhibiting glioma proliferation through the PI3K/AKT/mTOR signaling pathway based on network Pharmacology analysis

The mechanism of Bletilla striata inhibiting glioma proliferation through the PI3K/AKT/mTOR signaling pathway based on network Pharmacology analysis

Abstract This study aims to elucidate the potential mechanisms underlying the therapeutic effects of Bletilla striata in glioma. Targets of Bletilla striata and glioma were predicted using TCMSP, SwissTargetPrediction, GeneCards, and other databases. A “drug-ingredient-target” network and protein–pr...

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Bibliographic Details
Main Authors: Fenglian Ren, Yihua Wang, Changyang He, Xi Zheng, Chunyang Zhou, Xianmei Zhong
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Bletilla striata
Network pharmacology
Glioma
PI3K/AKT
Online Access:https://doi.org/10.1038/s41598-025-09081-0
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https://doi.org/10.1038/s41598-025-09081-0

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