A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions.

A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions.

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To eliminate vertical HIV transmission and achieve therapy-free viral suppression among children living with HIV, novel strategies beyond antiretroviral therapy (ART) are necessary. Our group previously identified a triple broadly neutralizing antibody (bNAb) combination comprising of 3BNC117, PGDM1...

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Bibliographic Details
Main Authors: Sedem Dankwa, Christina Kosman, Maria Dennis, Elena E Giorgi, Kenneth Vuong, Ioanna Pahountis, Ashley Garza, Christian Binuya, Janice McCarthy, Bryan T Mayer, Julia T Ngo, Chiamaka A Enemuo, Diane G Carnathan, Sherry Stanfield-Oakley, Stella J Berendam, Carolyn Weinbaum, Kathleen Engelman, Diogo M Magnani, Cliburn Chan, Guido Ferrari, Guido Silvestri, Rama R Amara, Ann Chahroudi, Sallie R Permar, Genevieve G Fouda, Ria Goswami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0312411&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0312411&type=printable

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