Cellular automata modelling of leukaemic stem cell dynamics in acute myeloid leukaemia: insights into predictive outcomes and targeted therapies

Acute myeloid leukaemia (AML) is a haematologic malignancy with high relapse rates in both adults and children. Leukaemic stem cells (LSCs) are central to leukaemopoiesis, treatment response and relapse and frequently associated with measurable residual disease (MRD). However, the dynamics of LSCs w...

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Bibliographic Details
Main Authors: Yutaka Saikawa, Toshihiko Komatsuzaki, Nobuaki Nishiyama, Toshihisa Hatta
Format: Article
Language:English
Published: The Royal Society 2025-01-01
Series:Royal Society Open Science
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Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.241202
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