Elucidating the Prognostic Role of BRAFV600E and the Activation Status of the Downstream MAPK Pathway in PTC: A Study from a Tertiary Centre in India

Elucidating the Prognostic Role of BRAFV600E and the Activation Status of the Downstream MAPK Pathway in PTC: A Study from a Tertiary Centre in India

Introduction: Papillary thyroid carcinoma (PTC) has an excellent prognosis, but few cases are treatment-resistant. To check the applicability of combined BRAFV600E and MEK-targeted therapy, the current study correlated BRAFV600E with the MAPK pathway activation status in a cohort of PTCs. The progno...

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Bibliographic Details
Main Authors: Nadeem Kocheri, Priti Chatterjee, Shipra Agarwal, Mehar C. Sharma, Sanjana Ballal, Chandrasekhar Bal, Sunil Chumber
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
brafv600e
ihc
mapk
papillary thyroid carcinoma
perk
pmek
Online Access:https://journals.lww.com/10.4103/ijem.ijem_235_23
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