Unraveling the immune mechanisms and therapeutic targets in lung adenosquamous transformation
Adenocarcinoma-to-squamous cell carcinoma transformation (AST) induces drug resistance in patients with lung adenocarcinoma (LUAD), often resulting in unfavorable clinical outcomes. In recent years, it has been found that alterations in the tumor immune microenvironment (TIME) during adenosquamous c...
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| Main Authors: | Haiyan Xu, Ying Yang, PingLi Wang, Shengnan Lin, Xiaochun Zhang, Huiwen Ni, Zhiyong Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1542526/full |
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