The Determination of Polymyxin B in Critically Ill Patients by the HPLC-MS/MS Method

Polymyxin B (PB) is a dose-dependent drug used to treat multidrug-resistantgram-negative bacteria, for which a suitable method is needed to determine clinical samples. A simple, economical, and efficient high-performance liquid chromatography-mass spectrometry (HPLC-MS/MS) method was developed and v...

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Bibliographic Details
Main Authors: Yirong Wang, Jingchun Chen, Jinpan Du, Liming Lei, Boxin Zhao, Yunpeng Bai, Dong Chen, Xipei Wang, Chunbo Chen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2023/6674009
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