The distribution of genetic polymorphism of CYP3A5, CYP3A4 and ABCB1 in patients subjected to renal transplantation

The distribution of genetic polymorphism of CYP3A5, CYP3A4 and ABCB1 in patients subjected to renal transplantation

Background/Aim. Polymorphisms of genes which encode transporter P-glycoprotein and most important enzymes for tacrolimus pharmacokinetics can have significant influence reflecting on blood concentrations of this drug. The aim of this study was to examine the distribution of polymorphisms of CYP3A5,...

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Main Authors: Vavić Neven, Rančić Nemanja, Cikota-Aleksić Bojana, Magić Zvonko, Cimeša Jelena, Obrenčević Katarina, Radojević Milorad, Mikov Momir, Dragojević-Simić Viktorija
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2016-01-01
Series:Vojnosanitetski Pregled
Subjects:
tacrolimus
kidney transplantation
polymorphism, genetic
CYP3A4 protein, human
CYP3A5 protein, human
ABCB1 protein, human
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600016V.pdf
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http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600016V.pdf

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