Rapid assessment of the osteogenic capacity of hydroxyapatite/aragonite using a murine tibial periosteal ossification model

Rapid assessment of the osteogenic capacity of hydroxyapatite/aragonite using a murine tibial periosteal ossification model

Biomaterials are widely used as orthopaedic implants and bone graft substitutes. We aimed to develop a rapid osteogenic assessment method using a murine tibial periosteal ossification model to evaluate the bone formation/remodelling potential of a biomaterial within 2–4 weeks. A novel hydroxyapatite...

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Main Authors: Emma Steijvers, Yunshong Shi, Hong Lu, Weixin Zhang, Yitian Zhang, Feihu Zhao, Baichuan Wang, Louise Hughes, Jake E. Barralet, Giulia Degli-Alessandrini, Igor Kraev, Richard Johnston, Zengwu Shao, Frank H. Ebetino, James T. Triffitt, R. Graham G. Russell, Davide Deganello, Xu Cao, Zhidao Xia
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Bioactive Materials
Subjects:
Osteogenesis assessment
Intramembranous ossification
Tibial periosteal bone formation
Hydroxyapatite/aragonite
Biomaterials
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24005097
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