Hypoxia-tolerant polymeric photosensitizer prodrug for cancer photo-immunotherapy

Abstract Although photodynamic immunotherapy represents a promising therapeutic approach against malignant tumors, its efficacy is often hampered by the hypoxia and immunosuppressive conditions within the tumor microenvironment (TME) following photodynamic therapy (PDT). In this study, we report the...

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Bibliographic Details
Main Authors: Jie Yu, Jiayan Wu, Jingsheng Huang, Cheng Xu, Mengke Xu, Clarence Zhi Han Koh, Kanyi Pu, Yan Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55529-8
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