Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages
In inflammation, the post-transcriptional regulation of transiently expressed genes provides a potential therapeutic target. Tristetraprolin (TTP) is of the factors regulating decay of cytokine mRNAs. The aim of the present study was to identify cytokines whose expression is regulated by TTP. We est...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2006-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/MI/2006/40691 |
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