Machine learning-based prediction of antipsychotic efficacy from brain gray matter structure in drug-naive first-episode schizophrenia

Abstract Predicting patient response to antipsychotic medication is a major challenge in schizophrenia treatment. This study investigates the predictive role of gray matter (GM) in short- and long-term treatment outcomes in drug-naive patients with first-episode schizophrenia (FES). A cohort of 104...

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Bibliographic Details
Main Authors: Xiaodong Guo, Enpeng Zhou, Xianghe Wang, Bingjie Huang, Tianqi Gao, Chengcheng Pu, Xin Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-025-00557-6
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