Polygenic transcriptome risk scores enhance predictive accuracy in atopic dermatitis

Polygenic transcriptome risk scores enhance predictive accuracy in atopic dermatitis

Abstract Background Incorporation of gene expression when estimating polygenic risk scores (PRS) in atopic dermatitis (AD) may provide additional insights in disease pathogenesis and enhance predictive accuracy. In this study, we developed polygenic transcriptome risk scores (PTRSs) derived from AD-...

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Main Authors: Charalabos Antonatos, Ashley Budu-Aggrey, Alexandros Pontikas, Adam Akritidis, Efstathia Pasmatzi, Aikaterini Tsiogka, Stamatis Gregoriou, Katerina Grafanaki, Lavinia Paternoster, Yiannis Vasilopoulos
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06570-8
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https://doi.org/10.1186/s12967-025-06570-8

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