Thionated levofloxacin derivative: Potential repurposing for cancer treatment and synergism with doxorubicin on doxorubicin-resistant lung cancer cells.

<h4>Objectives</h4>Fluoroquinolones, such as levofloxacin (LVX), are extended-spectrum drugs used for the treatment of bacterial infections. Several fluoroquinolone derivatives have shown promising antibacterial and anticancer activities. Our group has earlier synthesized and investigate...

Full description

Saved in:
Bibliographic Details
Main Authors: Hamza Abumansour, Osama H Abusara, Mohammad Abu-Sini, Wiam Khalil, Ali I M Ibrahim, Amal M Badawoud, Majed S Al Yami, Dina H Abulebdah, Shiraz Halloush
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0324930
Tags: Add Tag
No Tags, Be the first to tag this record!