Characterization of the growth-inhibitory and apoptosis-inducing activities of a triterpene saponin, securioside B against BAC1.2F5 macrophages

Characterization of the growth-inhibitory and apoptosis-inducing activities of a triterpene saponin, securioside B against BAC1.2F5 macrophages

Background: Since the growth state of macrophages in local pathological sites is considered a factor that regulates the processes of many disease, such as tumors, inflammation, and atherosclerosis, the substances that regulate macrophage growth or survival may be useful for disease control. We previ...

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Main Authors: Satoru Yui, Tomoya Kudo, Kazumi Hodono, Yoshihiro Mimaki, Minpei Kuroda, Yutaka Sashida, Masatoshi Yamazaki
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Mediators of Inflammation
Subjects:
Macrophages
Growth inhibition
Apoptosis
Securioside B
BAC1.2F5 cells
L-cell-conditioned medium
M-CSF
GM-CSF.
Online Access:http://dx.doi.org/10.1080/0962935031000134879
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http://dx.doi.org/10.1080/0962935031000134879

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