Estrogen receptor β activation alleviates inflammatory bowel disease by suppressing NLRP3-dependent IL-1β production in macrophages via downregulation of intracellular calcium level
Introduction: Although several estrogen receptor β (ERβ) agonists have been reported to alleviate IBD, the pivotal mechanism remains obscure. Objectives: To examine the effects and mechanisms of ERβ activation on cytokine/chemokine networks in colitis mice. Methods: Dextran sulfate sodium salt (DSS)...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
|
| Series: | Journal of Advanced Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2090123224002285 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|