A randomized, double-blind, placebo-controlled trial of niclosamide nanohybrid for the treatment of patients with mild to moderate COVID-19

Abstract Effective and reliable treatments for SARS-CoV-2 infections are a key part of global COVID-19 management. Based on vitro studies, niclosamide has been considered as a potential drug candidate for SARS-CoV-2, but its clinical development has been limited due to poor solubility and bioavailab...

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Main Authors: Jung Ho Kim, Sungmin Kym, Shin-Woo Kim, Dae Won Park, Ki Tae Kwon, Jun-Won Seo, Seungjin Yu, Goeun Choi, Sanoj Rejinold N, Jin-Ho Choy, Geun-woo Jin, Jun Yong Choi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62423-4
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