Auto-Induction in Oral Esketamine Treatment for Treatment-Resistant Depression: An Exploratory Study

Auto-Induction in Oral Esketamine Treatment for Treatment-Resistant Depression: An Exploratory Study

<b>Background:</b> Esketamine is a rapidly acting antidepressant with robust efficacy in treatment-resistant depression (TRD). Diminishing therapeutic effects and attenuated side effects have been reported after long-term use. This study aimed to investigate its long-term pharmacokinetic...

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Main Authors: Jolien K. E. Veraart, Cornelis F. Vos, Nieko C. Punt, Dylan Visser, Mireille A. Wessels, Sanne Y. Smith-Apeldoorn, Jeanine Kamphuis, Robert A. Schoevers, Daan J. Touw
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceuticals
Subjects:
esketamine
treatment-resistant depression
pharmacokinetics
auto-induction
Online Access:https://www.mdpi.com/1424-8247/18/5/627
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