Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway

Berberine alleviates atherosclerosis by modulating autophagy and inflammation through the RAGE-NF-κB pathway

IntroductionLipid accumulation and foam cell formation are significant features that expedite the progression of atherosclerosis (AS). Abnormal autophagy is a key factor in the development of AS. The importance of berberine (BBR) in AS has been well established. However, its exact role in regulating...

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Bibliographic Details
Main Authors: Peng Zhang, Meiying Jin, Lei Zhang, Yanjun Cui, Xiaokang Dong, Jie Yang, Jiayu Zhang, Haopeng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
atherosclerosis
berberine
autophagy
RAGE-NF-κB signaling pathway
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1540835/full
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