Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study

Background Verbal autopsy (VA), though imperfect, serves as a vital tool to determine cause-of-death, particularly for out-of-facility deaths, but challenges persist in integrating VA into Civil Registration and Vital Statistics systems. Objective To describe the challenges and successes of collecti...

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Main Authors: Monique Maqungo, Nadine Nannan, Beatrice Nojilana, Erin Nichols, Diane Morof, Mireille Cheyip, Chalapati Rao, Carl Lombard, Jessica Price, Kathleen Kahn, Lorna J. Martin, Francois Bezuidenhout, Ria Laubscher, Chodziwadziwa Kabudula, Tracy Glass, Oluwatoyin Awotiwon, Nesbert Zinyakatira, Noluntu Funani, Jané Joubert, Debbie Bradshaw, Pamela Groenewald
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Global Health Action
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Online Access:http://dx.doi.org/10.1080/16549716.2024.2399413
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author Monique Maqungo
Nadine Nannan
Beatrice Nojilana
Erin Nichols
Diane Morof
Mireille Cheyip
Chalapati Rao
Carl Lombard
Jessica Price
Kathleen Kahn
Lorna J. Martin
Francois Bezuidenhout
Ria Laubscher
Chodziwadziwa Kabudula
Tracy Glass
Oluwatoyin Awotiwon
Nesbert Zinyakatira
Noluntu Funani
Jané Joubert
Debbie Bradshaw
Pamela Groenewald
author_facet Monique Maqungo
Nadine Nannan
Beatrice Nojilana
Erin Nichols
Diane Morof
Mireille Cheyip
Chalapati Rao
Carl Lombard
Jessica Price
Kathleen Kahn
Lorna J. Martin
Francois Bezuidenhout
Ria Laubscher
Chodziwadziwa Kabudula
Tracy Glass
Oluwatoyin Awotiwon
Nesbert Zinyakatira
Noluntu Funani
Jané Joubert
Debbie Bradshaw
Pamela Groenewald
author_sort Monique Maqungo
collection DOAJ
description Background Verbal autopsy (VA), though imperfect, serves as a vital tool to determine cause-of-death, particularly for out-of-facility deaths, but challenges persist in integrating VA into Civil Registration and Vital Statistics systems. Objective To describe the challenges and successes of collecting a national sample of verbal autopsy interviews in South Africa to obtain the cause of death profile in 2017/18. Methods We recruited next of kin from 27 randomly selected sub-districts (10.5%) across South Africa between September 2017 and April 2018. Trained fieldworkers conducted face-to-face interviews using the WHO2016 VA instrument, with physicians certifying underlying causes of death. Feasibility was evaluated based on response rates, participation, and data quality. Results Of the total 36,976 deaths registered, only 26% were identified during recruitment, with a 55% overall response rate for VA interviews. Physician-reviewed VA data were deemed of good quality for assigning underlying causes of death in 83% of cases. By comparing cause-specific mortality fractions, physician-reviewed VA identified 22.3% HIV/AIDS and InterVA-5 identified 18.5%, aligning with burden of disease estimates, while Statistics South Africa reported 4.9% HIV/AIDS. Conclusions The study demonstrated the feasibility of using VA on a national scale, but immense challenges in identifying and recruiting next of kin highlight the importance of formalising VAs within the country’s death notification system.
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spelling doaj-art-6517750a785f4c109c4c41b4514aa0382025-02-05T12:46:14ZengTaylor & Francis GroupGlobal Health Action1654-98802024-12-0117110.1080/16549716.2024.23994132399413Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation studyMonique Maqungo0Nadine Nannan1Beatrice Nojilana2Erin Nichols3Diane Morof4Mireille Cheyip5Chalapati Rao6Carl Lombard7Jessica Price8Kathleen Kahn9Lorna J. Martin10Francois Bezuidenhout11Ria Laubscher12Chodziwadziwa Kabudula13Tracy Glass14Oluwatoyin Awotiwon15Nesbert Zinyakatira16Noluntu Funani17Jané Joubert18Debbie Bradshaw19Pamela Groenewald20South African Medical Research CouncilSouth African Medical Research CouncilSouth African Medical Research CouncilU.S. Centers for Disease Control and PreventionU.S. Public Health Service Commissioned CorpsCenters for Disease Control and PreventionAustralian National UniversitySouth African Medical Research Council, Parow Valley, Western Cape, South AfricaUniversity of the WitwatersrandUniversity of the WitwatersrandUniversity of Cape TownGeoSpace InternationalSouth African Medical Research Council, Parow Valley, Western Cape, South AfricaUniversity of the WitwatersrandSouth African Medical Research CouncilSouth African Medical Research CouncilWestern Cape Department of HealthSouth African Medical Research CouncilSouth African Medical Research CouncilSouth African Medical Research CouncilSouth African Medical Research CouncilBackground Verbal autopsy (VA), though imperfect, serves as a vital tool to determine cause-of-death, particularly for out-of-facility deaths, but challenges persist in integrating VA into Civil Registration and Vital Statistics systems. Objective To describe the challenges and successes of collecting a national sample of verbal autopsy interviews in South Africa to obtain the cause of death profile in 2017/18. Methods We recruited next of kin from 27 randomly selected sub-districts (10.5%) across South Africa between September 2017 and April 2018. Trained fieldworkers conducted face-to-face interviews using the WHO2016 VA instrument, with physicians certifying underlying causes of death. Feasibility was evaluated based on response rates, participation, and data quality. Results Of the total 36,976 deaths registered, only 26% were identified during recruitment, with a 55% overall response rate for VA interviews. Physician-reviewed VA data were deemed of good quality for assigning underlying causes of death in 83% of cases. By comparing cause-specific mortality fractions, physician-reviewed VA identified 22.3% HIV/AIDS and InterVA-5 identified 18.5%, aligning with burden of disease estimates, while Statistics South Africa reported 4.9% HIV/AIDS. Conclusions The study demonstrated the feasibility of using VA on a national scale, but immense challenges in identifying and recruiting next of kin highlight the importance of formalising VAs within the country’s death notification system.http://dx.doi.org/10.1080/16549716.2024.2399413cause of deathcause-specific mortality fractionscivil registration and vital statisticsverbal autopsysouth africa
spellingShingle Monique Maqungo
Nadine Nannan
Beatrice Nojilana
Erin Nichols
Diane Morof
Mireille Cheyip
Chalapati Rao
Carl Lombard
Jessica Price
Kathleen Kahn
Lorna J. Martin
Francois Bezuidenhout
Ria Laubscher
Chodziwadziwa Kabudula
Tracy Glass
Oluwatoyin Awotiwon
Nesbert Zinyakatira
Noluntu Funani
Jané Joubert
Debbie Bradshaw
Pamela Groenewald
Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study
Global Health Action
cause of death
cause-specific mortality fractions
civil registration and vital statistics
verbal autopsy
south africa
title Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study
title_full Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study
title_fullStr Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study
title_full_unstemmed Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study
title_short Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study
title_sort can verbal autopsies be used on a national scale key findings and lessons from south africa s national cause of death validation study
topic cause of death
cause-specific mortality fractions
civil registration and vital statistics
verbal autopsy
south africa
url http://dx.doi.org/10.1080/16549716.2024.2399413
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