Effects of antifoam agents on Spodoptera frugiperda 9 cell growth and baculovirus infection dynamics

Abstract The baculovirus expression system is widely used for recombinant protein production. However, its scalability under shaking or stirring cultivation conditions remains a challenge due to foam formation which can negatively affect cell metabolism and viability, complicate process control, and...

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Bibliographic Details
Main Authors: Kristina Worch, Merlin Krause, Antje Burse
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-025-00516-w
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