Functional analysis of promoter element 2 within the viral polymerase gene of an emerging paramyxovirus, Sosuga virus

Functional analysis of promoter element 2 within the viral polymerase gene of an emerging paramyxovirus, Sosuga virus

ABSTRACT Paramyxovirus genomes carry bipartite promoters at the 3′ ends of both their genome and antigenome, thereby initiating RNA synthesis, which requires the viral polymerase to recognize two elements: the primary promoter element 1 (PE1) and the secondary promoter element 2 (PE2). We have previ...

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Bibliographic Details
Main Authors: Lipi Akter, Junna Kawasaki, Tofazzal Md. Rakib, Takashi Okura, Fumihiro Kato, Shohei Kojima, Kosuke Oda, Yusuke Matsumoto
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
negative-strand RNA virus
paramyxovirus
promoters
RNA polymerases
viral replication
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00534-25
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https://journals.asm.org/doi/10.1128/spectrum.00534-25

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