Rapid degradation of DHX36 revealing its transcriptional role by interacting with G‐quadruplex

Rapid degradation of DHX36 revealing its transcriptional role by interacting with G‐quadruplex

Abstract Accumulating evidence indicates that G‐quadruplexes (G4s) are involved in transcriptional regulation. Previous studies have demonstrated that DHX36 preferentially resolves G4s, suggesting its potential impact on gene transcription mediated by these structures. However, systematic validation...

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Bibliographic Details
Main Authors: Ziang Lu, Jinglei Xu, Yuqi Chen, Yuanyuan Zhou, Xiaolu Zhou, Qi Wang, Qi Wei, Shaoqing Han, Ruiqi Zhao, Xiaocheng Weng, Xiaolian Zhang, Xiang Zhou
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Aggregate
Subjects:
G‐quadruplex
nascent RNA
protein degradation
transcription
Online Access:https://doi.org/10.1002/agt2.647
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