Bacterial evolution of antibiotic hypersensitivity

Bacterial evolution of antibiotic hypersensitivity

Abstract The evolution of resistance to a single antibiotic is frequently accompanied by increased resistance to multiple other antimicrobial agents. In sharp contrast, very little is known about the frequency and mechanisms underlying collateral sensitivity. In this case, genetic adaptation under a...

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Main Authors: Viktória Lázár, Gajinder Pal Singh, Réka Spohn, István Nagy, Balázs Horváth, Mónika Hrtyan, Róbert Busa‐Fekete, Balázs Bogos, Orsolya Méhi, Bálint Csörgő, György Pósfai, Gergely Fekete, Balázs Szappanos, Balázs Kégl, Balázs Papp, Csaba Pál
Format: Article
Language:English
Published: Springer Nature 2013-10-01
Series:Molecular Systems Biology
Subjects:
antibiotic resistance
collateral sensitivity network
evolutionary experiment
trade off
Online Access:https://doi.org/10.1038/msb.2013.57
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https://doi.org/10.1038/msb.2013.57

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