Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression

Abstract Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been fully understood. Here, we report a role of nuclear ANLN in gene transcriptional regulation...

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Main Authors: Yu-Fei Cao, Hui Wang, Yong Sun, Bei-Bei Tong, Wen-Qi Shi, Liu Peng, Yi-Meng Zhang, Yu-Qiu Wu, Teng Fu, Hua-Yan Zou, Kai Zhang, Li-Yan Xu, En-Min Li
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56645-9
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