Characterizing the evolution of lesion, penumbra and blood-brain barrier permeability in a photothrombotic juvenile rat stroke model using MRI and histology

Abstract Pediatric stroke is a significant cause of childhood mortality and morbidity. The clinical research in this field bears certain limitations that do not exist in the pre-clinical setting. Experimental models of ischemic stroke show differences in lesion evolution and blood-brain barrier (BBB...

Full description

Saved in:
Bibliographic Details
Main Authors: Trish Domi, Faraz Honarvar, Daniel Sare, Mahmoud Slim, Nomazulu Dlamini, Andrea Kassner
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-87902-y
Tags: Add Tag
No Tags, Be the first to tag this record!