Resting Ca2+ fluxes protect cells from fast mitochondrial fragmentation, cell stress responses, and immediate transcriptional reprogramming

Abstract Homeostatic calcium ion (Ca2+) fluxes between the endoplasmic reticulum, cytosol, and extracellular space occur not only in response to cell stimulation but also in unstimulated cells. Using murine astrocytes as a model, we asked whether there is a signaling function of these resting Ca2+ f...

Full description

Saved in:
Bibliographic Details
Main Authors: Caroline Fecher, Annemarie Sodmann, Felicitas Schlott, Juliane Jaepel, Franziska Schmitt, Isabella Lengfelder, Thorsten Bischler, Bernhard Nieswandt, Konstanze F. Winklhofer, Robert Blum
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Cellular and Molecular Life Sciences
Subjects:
Online Access:https://doi.org/10.1007/s00018-025-05745-2
Tags: Add Tag
No Tags, Be the first to tag this record!