Characterization and dosimetric predictors for absolute lymphocyte count changes during neoadjuvant chemoradiotherapy with or without pembrolizumab for esophageal squamous cell carcinoma: an analysis of a prospective cohort

Characterization and dosimetric predictors for absolute lymphocyte count changes during neoadjuvant chemoradiotherapy with or without pembrolizumab for esophageal squamous cell carcinoma: an analysis of a prospective cohort

Abstract Aim To characterize the differences of dynamic changes for absolute lymphocyte count (ALC) among esophageal squamous cell carcinoma (ESCC) patients treated with neoadjuvant chemoradiotherapy (nCRT) with or without pembrolizumab, as well as to investigate the clinical and lymphocyte-related...

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Main Authors: Wei-Xiang Qi, Shuyan Li, Shujun Zhang, Chao Li, Huan Li, Xiaomei Li, Chaofen Zhao, Gang Cai, Cheng Xu, Xuan Han, Yibin Zhang, Jiayi Chen, Shengguang Zhao
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Radiation Oncology
Subjects:
Lymphocyte-related organs at risk
Neoadjuvant chemoradiotherapy
Esophageal squamous cell carcinoma
Pembrolizumab
Online Access:https://doi.org/10.1186/s13014-024-02581-9
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https://doi.org/10.1186/s13014-024-02581-9

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