Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

IntroductionIn mammals, Paneth cells, located in the crypts of the small intestine, produceantimicrobial peptides that serve to keep the intestinal microbiome under control. a-Defensins are the primary antimicrobial peptides produced by these cells.MethodsWe used 148 publicly available bulk RNA-seq...

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Bibliographic Details
Main Authors: Steven Timmermans, Charlotte Wallaeys, Somara De Beul, Natalia Garcia-Gonzales, Claude Libert
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1543059/full
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