A Clinical Nomogram for Predicting Substandard Serum Valproic Acid Concentrations in Chinese Patients With Epilepsy

A Clinical Nomogram for Predicting Substandard Serum Valproic Acid Concentrations in Chinese Patients With Epilepsy

ABSTRACT: Background: It is well-known that substandard serum valproic acid (VPA) concentrations may lead to treatment failure of epilepsy. However, there is still a lack of a quick method to predict whether a patient's serum VPA concentration will reach the standard. Objective: The aims of th...

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Main Authors: Zi-Hao Duan, MS, Chun-Yuan He, MS, Jie Chen, BS, Jun-Jie Jiang, BS, Zhi-Xiang Zhu, PhD, Jing Li, MS, Fa-Cai Wang, MD
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Therapeutic Research
Subjects:
epilepsy
influencing factors
nomogram
risk prediction model
serum drug concentration
valproic acid (VPA)
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X24000419
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