2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism
Background and Aims. 2D-shear wave elastography (2D-SWE) is a relatively new elastographic technique. The aim of the present study is to determine the values of the elasticity indexes (EI) measured by 2D-SWE in parathyroid benign lesions (adenomas or hyperplasia) and to establish if this investigati...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2017/9092120 |
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| author | Ioana Golu Ioan Sporea Lavinia Moleriu Anca Tudor Marioara Cornianu Adrian Vlad Romulus Timar Melania Balas Daniela Amzar Mihaela Vlad |
| author_facet | Ioana Golu Ioan Sporea Lavinia Moleriu Anca Tudor Marioara Cornianu Adrian Vlad Romulus Timar Melania Balas Daniela Amzar Mihaela Vlad |
| author_sort | Ioana Golu |
| collection | DOAJ |
| description | Background and Aims. 2D-shear wave elastography (2D-SWE) is a relatively new elastographic technique. The aim of the present study is to determine the values of the elasticity indexes (EI) measured by 2D-SWE in parathyroid benign lesions (adenomas or hyperplasia) and to establish if this investigation is helpful for the preoperative identification of the parathyroid adenoma. Material and Methods. The study groups were represented by 22 patients with primary or tertiary hyperparathyroidism, diagnosed by specific tests, and 43 healthy controls, in whom the thyroid parenchyma was evaluated, in order to compare the EI of the thyroid tissue with those of the parathyroid lesions. Results. The mean EI measured by 2D-SWE in the parathyroid lesions was 10.2 ± 4.9 kPa, significantly lower than that of the normal thyroid parenchyma (19.5 ± 7.6 kPa; p=0.007), indicating soft tissue. For a cutoff value of 12.5 kPa, the EI assessed by 2D-SWE had a sensitivity of 93% and a specificity of 86% (AUC = 0.949; p<0.001) for predicting parathyroid lesions. Conclusion. A value lower than 12.5 kPa for the mean EI measured by 2D-SWE can be used to confirm that the lesion/nodule is a parathyroid adenoma. |
| format | Article |
| id | doaj-art-643c1ecddb8145cb8b8df84330a8c072 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-643c1ecddb8145cb8b8df84330a8c0722025-02-03T01:09:49ZengWileyInternational Journal of Endocrinology1687-83371687-83452017-01-01201710.1155/2017/909212090921202D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with HyperparathyroidismIoana Golu0Ioan Sporea1Lavinia Moleriu2Anca Tudor3Marioara Cornianu4Adrian Vlad5Romulus Timar6Melania Balas7Daniela Amzar8Mihaela Vlad9Department of Endocrinology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaElastography Center, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Biostatistics and Medical Informatics, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Biostatistics and Medical Informatics, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Pathology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaElastography Center, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Diabetes and Metabolic Diseases, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Endocrinology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Endocrinology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaDepartment of Endocrinology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, RomaniaBackground and Aims. 2D-shear wave elastography (2D-SWE) is a relatively new elastographic technique. The aim of the present study is to determine the values of the elasticity indexes (EI) measured by 2D-SWE in parathyroid benign lesions (adenomas or hyperplasia) and to establish if this investigation is helpful for the preoperative identification of the parathyroid adenoma. Material and Methods. The study groups were represented by 22 patients with primary or tertiary hyperparathyroidism, diagnosed by specific tests, and 43 healthy controls, in whom the thyroid parenchyma was evaluated, in order to compare the EI of the thyroid tissue with those of the parathyroid lesions. Results. The mean EI measured by 2D-SWE in the parathyroid lesions was 10.2 ± 4.9 kPa, significantly lower than that of the normal thyroid parenchyma (19.5 ± 7.6 kPa; p=0.007), indicating soft tissue. For a cutoff value of 12.5 kPa, the EI assessed by 2D-SWE had a sensitivity of 93% and a specificity of 86% (AUC = 0.949; p<0.001) for predicting parathyroid lesions. Conclusion. A value lower than 12.5 kPa for the mean EI measured by 2D-SWE can be used to confirm that the lesion/nodule is a parathyroid adenoma.http://dx.doi.org/10.1155/2017/9092120 |
| spellingShingle | Ioana Golu Ioan Sporea Lavinia Moleriu Anca Tudor Marioara Cornianu Adrian Vlad Romulus Timar Melania Balas Daniela Amzar Mihaela Vlad 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism International Journal of Endocrinology |
| title | 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism |
| title_full | 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism |
| title_fullStr | 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism |
| title_full_unstemmed | 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism |
| title_short | 2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism |
| title_sort | 2d shear wave elastography in the evaluation of parathyroid lesions in patients with hyperparathyroidism |
| url | http://dx.doi.org/10.1155/2017/9092120 |
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