Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains

Antibodies are a popular and powerful class of therapeutic due to their ability to exhibit high affinity and specificity to target proteins. However, the majority of antibody therapeutics are not genetically human, with initial therapeutic designs typically obtained from animal models. Humanization...

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Bibliographic Details
Main Authors: Lewis Chinery, Jeliazko R. Jeliazkov, Charlotte M. Deane
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:mAbs
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2024.2434121
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