Precision targeting of androgen receptor–ferroptosis crosstalk in prostate cancer: From mechanisms to therapeutic strategies

Ferroptosis, an iron-dependent form of regulated cell death characterized by lipid peroxidation, has emerged as a promising vulnerability in cancer therapy. In prostate cancer (PCa), androgen receptor (AR) signaling remains a central oncogenic driver, with androgen deprivation therapy (ADT) as the s...

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Bibliographic Details
Main Authors: Dongfang Lv, Yankang Shi, Luan Kou, Denglu Zhang, Yanxia Guo, Shengtian Zhao
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Pharmacological Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825003408
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